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GcMAF Research Papers

There are 46 major GcMAF research papers by over 100 eminent scientists published on the American Government’s Pubmed system alone.

 

1. Effects of Vitamin D-binding Protein-derived Macrophage-activating Factor on Human Breast Cancer Cells.

Pacini S, Punzi T, Morucci G, Gulisano M, Ruggiero M. Anticancer Res. 2012 Jan;32(1):45-52. PMID: 22213287 [PubMed – in process] Related citations

2. Effect of paricalcitol and GcMAF on angiogenesis and human peripheral blood mononuclear cell proliferation and signaling.

Pacini S, Morucci G, Punzi T, Gulisano M, Ruggiero M, Amato M, Aterini S.

J Nephrol. 2011 Sep 26:0. doi: 10.5301/jn.5000035. [Epub ahead of print]

PMID: 21956771 [PubMed – as supplied by publisher] Related citations

3. Effect of the Gc-derived macrophage-activating factor precursor (preGcMAF) on phagocytic activation of mouse peritoneal macrophages.

Uto Y, Yamamoto S, Takeuchi R, Nakagawa Y, Hirota K, Terada H, Onizuka S, Nakata E, Hori H.

Anticancer Res. 2011 Jul;31(7):2489-92.

PMID: 21873164 [PubMed – indexed for MEDLINE] Related citations

4. Phenotype of Gc-globulin influences the macrophage activating factor (MAF) levels in serum.

Debruyne E, Speeckaert M, Weygaerde YV, Delanghe J.

Clin Chem Lab Med. 2011 Nov;49(11):1855-60. Epub 2011 Aug 23.

PMID: 21859424 [PubMed – in process] Related citations

5. Gc protein-derived macrophage-activating factor (GcMAF) stimulates cAMP formation in human mononuclear cells and inhibits angiogenesis in chick embryo chorionallantoic membrane assay.

Pacini S, Morucci G, Punzi T, Gulisano M, Ruggiero M.

Cancer Immunol Immunother. 2011 Apr;60(4):479-85. Epub 2010 Dec 14.

PMID: 21170647 [PubMed – indexed for MEDLINE] Related citations

6. Vitamin D binding protein-macrophage activating factor directly inhibits proliferation, migration, and uPAR expression of prostate cancer cells.

Gregory KJ, Zhao B, Bielenberg DR, Dridi S, Wu J, Jiang W, Huang B, Pirie-Shepherd S, Fannon M.

PLoS One. 2010 Oct 18;5(10):e13428.

PMID: 20976141 [PubMed – indexed for MEDLINE] Free PMC ArticleRelated citations

7. Vitamin D Binding Protein-Macrophage Activating Factor Inhibits HCC in SCID Mice.

Nonaka K, Onizuka S, Ishibashi H, Uto Y, Hori H, Nakayama T, Matsuura N, Kanematsu T, Fujioka H.

J Surg Res. 2012 Jan;172(1):116-22. Epub 2010 Sep 17.

PMID: 20855083 [PubMed – in process] Related citations

8. The glycosylation and characterization of the candidate Gc macrophage activating factor.

Ravnsborg T, Olsen DT, Thysen AH, Christiansen M, Houen G, Højrup P.

Biochim Biophys Acta. 2010 Apr;1804(4):909-17. Epub 2010 Jan 13.

PMID: 20079467 [PubMed – indexed for MEDLINE] Related citations

9. Glycosylation status of vitamin D binding protein in cancer patients.

Rehder DS, Nelson RW, Borges CR.

Protein Sci. 2009 Oct;18(10):2036-42.

PMID: 19642159 [PubMed – indexed for MEDLINE] Free PMC ArticleRelated citations

10. Vitamin D binding protein genotype and osteoporosis.

Fang Y, van Meurs JB, Arp P, van Leeuwen JP, Hofman A, Pols HA, Uitterlinden AG.

Calcif Tissue Int. 2009 Aug;85(2):85-93. Epub 2009 Jun 2.

PMID: 19488670 [PubMed – indexed for MEDLINE] Free PMC ArticleRelated citations

11. Immunotherapy of HIV-infected patients with Gc protein-derived macrophage activating factor (GcMAF).

Yamamoto N, Ushijima N, Koga Y.

J Med Virol. 2009 Jan;81(1):16-26.

PMID: 19031451 [PubMed – indexed for MEDLINE] Related citations

12. Immunotherapy for Prostate Cancer with Gc Protein-Derived Macrophage-Activating Factor, GcMAF.

Yamamoto N, Suyama H, Yamamoto N.

Transl Oncol. 2008 Jul;1(2):65-72.

PMID: 18633461 [PubMed] Free PMC ArticleRelated citations

13. Modulation of protein stability by O-glycosylation in a designed Gc-MAF analog.

Spiriti J, Bogani F, van der Vaart A, Ghirlanda G.

Biophys Chem. 2008 May;134(3):157-67. Epub 2008 Feb 21.

PMID: 18329161 [PubMed – indexed for MEDLINE] Related citations

14. Immunotherapy of metastatic colorectal cancer with vitamin D-binding protein-derived macrophage-activating factor, GcMAF.

Yamamoto N, Suyama H, Nakazato H, Yamamoto N, Koga Y.

Cancer Immunol Immunother. 2008 Jul;57(7):1007-16.

PMID: 18058096 [PubMed – indexed for MEDLINE] Related citations

15. Immunotherapy of metastatic breast cancer patients with vitamin D-binding protein-derived macrophage activating factor (GcMAF).

Yamamoto N, Suyama H, Yamamoto N, Ushijima N.

Int J Cancer. 2008 Jan 15;122(2):461-7.

PMID: 17935130 [PubMed – indexed for MEDLINE] Related citations

16. A designed glycoprotein analogue of Gc-MAF exhibits native-like phagocytic activity.

Bogani F, McConnell E, Joshi L, Chang Y, Ghirlanda G.

J Am Chem Soc. 2006 Jun 7;128(22):7142-3.

PMID: 16734450 [PubMed – indexed for MEDLINE] Related citations

17. Inhibition of angiogenesis by vitamin D-binding protein: characterization of anti-endothelial activity of DBP-maf.

Kalkunte S, Brard L, Granai CO, Swamy N.

Angiogenesis. 2005;8(4):349-60. Epub 2006 Jan 7.

PMID: 16400520 [PubMed – indexed for MEDLINE] Related citations

18. Gc protein (vitamin D-binding protein): Gc genotyping and GcMAF precursor activity.

Nagasawa H, Uto Y, Sasaki H, Okamura N, Murakami A, Kubo S, Kirk KL, Hori H.

Anticancer Res. 2005 Nov-Dec;25(6A):3689-95. Review.

PMID: 16302727 [PubMed – indexed for MEDLINE] Related citations

19. Association of the macrophage activating factor (MAF) precursor activity with polymorphism in vitamin D-binding protein.

Nagasawa H, Sasaki H, Uto Y, Kubo S, Hori H.

Anticancer Res. 2004 Sep-Oct;24(5C):3361-6.

PMID: 15515432 [PubMed – indexed for MEDLINE] Related citations

20. Female premenopausal fracture risk is associated with gc phenotype.

Lauridsen AL, Vestergaard P, Hermann AP, Moller HJ, Mosekilde L, Nexo E.

J Bone Miner Res. 2004 Jun;19(6):875-81. Epub 2004 Jan 27.

PMID: 15125786 [PubMed – indexed for MEDLINE] Related citations

21. Pancreatic carcinogenesis: apoptosis and angiogenesis.

Onizuka S, Kawakami S, Taniguchi K, Fujioka H, Miyashita K.

Pancreas. 2004 Apr;28(3):317-9.

PMID: 15084979 [PubMed – indexed for MEDLINE] Related citations

22. Effect of salivary gland adenocarcinoma cell-derived alpha-N-acetylgalactosaminidase on the bioactivity of macrophage activating factor.

Matsuura T, Uematsu T, Yamaoka M, Furusawa K.

Int J Oncol. 2004 Mar;24(3):521-8.

PMID: 14767536 [PubMed – indexed for MEDLINE] Related citations

23. The anabolic effects of vitamin D-binding protein-macrophage activating factor (DBP-MAF) and a novel small peptide on bone.

Schneider GB, Grecco KJ, Safadi FF, Popoff SN.

Crit Rev Eukaryot Gene Expr. 2003;13(2-4):277-84.

PMID: 14696974 [PubMed – indexed for MEDLINE] Related citations

24. Gc protein-derived macrophage activating factor (GcMAF): isoelectric focusing pattern and tumoricidal activity.

Mohamad SB, Nagasawa H, Sasaki H, Uto Y, Nakagawa Y, Kawashima K, Hori H.

Anticancer Res. 2003 Nov-Dec;23(6a):4451-7.

PMID: 14666733 [PubMed – indexed for MEDLINE] Related citations

25. Mitogen-activated protein kinase pathway mediates DBP-maf-induced apoptosis in RAW 264.7 macrophages.

Gumireddy K, Reddy CD, Swamy N.

J Cell Biochem. 2003 Sep 1;90(1):87-96.

PMID: 12938159 [PubMed – indexed for MEDLINE] Related citations

26. Vitamin D binding protein-macrophage activating factor (DBP-maf) inhibits angiogenesis and tumor growth in mice.

Kisker O, Onizuka S, Becker CM, Fannon M, Flynn E, D’Amato R, Zetter B, Folkman J, Ray R, Swamy N, Pirie-Shepherd S.

Neoplasia. 2003 Jan-Feb;5(1):32-40.

PMID: 12659668 [PubMed – indexed for MEDLINE]Free PMC ArticleRelated citations

27. Characterization of human Gc protein-derived macrophage activation factor (GcMAF) and its functional role in macrophage tumoricidal activity.

Mohamad SB, Hori H, Nagasawa H, Usui K, Uto Y.

Adv Exp Med Biol. 2003;510:77-82. No abstract available.

PMID: 12580408 [PubMed – indexed for MEDLINE] Related citations

28. Preparation of Gc protein-derived macrophage activating factor (GcMAF) and its structural characterization and biological activities.

Mohamad SB, Nagasawa H, Uto Y, Hori H.

Anticancer Res. 2002 Nov-Dec;22(6C):4297-300.

PMID: 12553073 [PubMed – indexed for MEDLINE] Related citations

29. Effects of vitamin D(3)-binding protein-derived macrophage activating factor (GcMAF) on angiogenesis.

Kanda S, Mochizuki Y, Miyata Y, Kanetake H, Yamamoto N.

J Natl Cancer Inst. 2002 Sep 4;94(17):1311-9.

PMID: 12208896 [PubMed – indexed for MEDLINE] Free ArticleRelated citations

30. Tumor cell alpha-N-acetylgalactosaminidase activity and its involvement in GcMAF-related macrophage activation.

Mohamad SB, Nagasawa H, Uto Y, Hori H.

Comp Biochem Physiol A Mol Integr Physiol. 2002 May;132(1):1-8.

PMID: 12062184 [PubMed – indexed for MEDLINE] Related citations

31. Baculovirus-expressed vitamin D-binding protein-macrophage activating factor (DBP-maf) activates osteoclasts and binding of 25-hydroxyvitamin D(3) does not influence this activity.

Swamy N, Ghosh S, Schneider GB, Ray R.

J Cell Biochem. 2001;81(3):535-46.

PMID: 11255236 [PubMed – indexed for MEDLINE] Related citations

32. Lectin immunoassay for macrophage-activating factor (Gc-MAF) produced by deglycosylation of Gc-globulin: evidence for noninducible generation of Gc-MAF.

Kanan RM, Cook DB, Datta HK.

Clin Chem. 2000 Mar;46(3):412-4. No abstract available.

PMID: 10702530 [PubMed – indexed for MEDLINE] Free ArticleRelated citations

33. The toothless osteopetrotic rat has a normal vitamin D-binding protein-macrophage activating factor (DBP-MAF) cascade and chondrodysplasia resistant to treatments with colony stimulating factor-1 (CSF-1) and/or DBP-MAF.

Odgren PR, Popoff SN, Safadi FF, MacKay CA, Mason-Savas A, Seifert MF, Marks SC Jr.

Bone. 1999 Aug;25(2):175-81. PMID: 10456382 [PubMed – indexed for MEDLINE]

34. Evidence for continuous basel generation of GC-MAF: absence in infantile osteopetrosis and restoration after bone marrow transplant.

Datta HK, Cook DB, Kanan RM.

Blood. 1999 Jun 1;93(11):4026-7. No abstract available.

PMID: 10383196 [PubMed – indexed for MEDLINE] Free ArticleRelated citations

35. Antitumor effect of vitamin D-binding protein-derived macrophage activating factor on Ehrlich ascites tumor-bearing mice.

Koga Y, Naraparaju VR, Yamamoto N.

Proc Soc Exp Biol Med. 1999 Jan;220(1):20-6.

PMID: 9893164 [PubMed – indexed for MEDLINE] Related citations

36. A possible new role for vitamin D-binding protein in osteoclast control: inhibition of extracellular Ca2+ sensing at low physiological concentrations.

Adebanjo OA, Moonga BS, Haddad JG, Huang CL, Zaidi M.

Biochem Biophys Res Commun. 1998 Aug 28;249(3):668-71.

PMID: 9731194 [PubMed – indexed for MEDLINE] Related citations

37. Structurally well-defined macrophage activating factor derived from vitamin D3-binding protein has a potent adjuvant activity for immunization.

Yamamoto N, Naraparaju VR.

Immunol Cell Biol. 1998 Jun;76(3):237-44.

PMID: 9682967 [PubMed – indexed for MEDLINE] Free ArticleRelated citations

38. Immunotherapy of BALB/c mice bearing Ehrlich ascites tumor with vitamin D-binding protein-derived macrophage activating factor.

Yamamoto N, Naraparaju VR.

Cancer Res. 1997 Jun 1;57(11):2187-92.

PMID: 9187119 [PubMed – indexed for MEDLINE] Free ArticleRelated citations

39. Deglycosylation of serum vitamin D3-binding protein by alpha-N-acetylgalactosaminidase detected in the plasma of patients with systemic lupus erythematosus.

Yamamoto N, Naraparaju VR, Moore M, Brent LH.

Clin Immunol Immunopathol. 1997 Mar;82(3):290-8.

PMID: 9073553 [PubMed – indexed for MEDLINE]Related citations

40. Macrophage-directed immunotherapy as adjuvant to photodynamic therapy of cancer.

Korbelik M, Naraparaju VR, Yamamoto N.

Br J Cancer. 1997;75(2):202-7.

PMID: 9010027 [PubMed – indexed for MEDLINE] Free PMC Article

41. The effects of vitamin D binding protein-macrophage activating factor and colony-stimulating factor-1 on hematopoietic cells in normal and osteopetrotic rats.

Benis KA, Schneider GB.

Blood. 1996 Oct 15;88(8):2898-905.

PMID: 8874186 [PubMed – indexed for MEDLINE] Free ArticleRelated citations

42. Structural definition of a potent macrophage activating factor derived from vitamin D3-binding protein with adjuvant activity for antibody production.

Yamamoto N.

Mol Immunol. 1996 Oct;33(15):1157-64.

PMID: 9070663 [PubMed – indexed for MEDLINE] Related citations

43. Deglycosylation of serum vitamin D3-binding protein leads to immunosuppression in cancer patients.

Yamamoto N, Naraparaju VR, Asbell SO.

Cancer Res. 1996 Jun 15;56(12):2827-31. PMID: 8665521 [PubMed – indexed for MEDLINE]

44. Structural modification of serum vitamin D3-binding protein and immunosuppression in AIDS patients.

Yamamoto N, Naraparaju VR, Srinivasula SM.

AIDS Res Hum Retroviruses. 1995 Nov;11(11):1373-8.

PMID: 8573395 [PubMed – indexed for MEDLINE] Related citations

45. Effects of vitamin D binding protein-macrophage activating factor (DBP-MAF) infusion on bone resorption in two osteopetrotic mutations.

Schneider GB, Benis KA, Flay NW, Ireland RA, Popoff SN.

Bone. 1995 Jun;16(6):657-62.

PMID: 7669443 [PubMed – indexed for MEDLINE] Related citations

46. A defect in the inflammation-primed macrophage-activation cascade in osteopetrotic rats.

Yamamoto N, Lindsay DD, Naraparaju VR, Ireland RA, Popoff SN.

J Immunol. 1994 May 15;152(10):5100-7.

PMID:

8176226 [PubMed – indexed for MEDLINE] Related citations

David Noakes  1st February 2012

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